/* Template A — National (Peptide). Clean / clinical / authoritative.
   Hand-authored design system (no framework). Palette approved 2026-06-08. */

:root{
  --pa-teal:#0E7C86; --pa-teal-700:#0a5f67; --pa-teal-050:#e6f3f4;
  --pa-ink:#0F172A; --pa-ink-700:#1e293b; --pa-slate:#475569; --pa-slate-400:#94a3b8;
  --pa-violet:#6D5AE6; --pa-violet-700:#5a47cf; --pa-violet-050:#efedfc;
  --pa-surface:#F8FAFC; --pa-white:#ffffff; --pa-border:#E2E8F0;
  --pa-green:#16A34A; --pa-amber:#D97706;
  --pa-radius:14px; --pa-radius-sm:10px; --pa-shadow:0 1px 2px rgba(15,23,42,.04),0 8px 24px rgba(15,23,42,.06);
  --pa-maxw:1160px; --pa-font:"Inter",system-ui,-apple-system,Segoe UI,Roboto,Helvetica,Arial,sans-serif;
  --pa-serif:"Source Serif 4",Georgia,"Times New Roman",serif;
}

*,*::before,*::after{box-sizing:border-box}
html{-webkit-text-size-adjust:100%}
body{margin:0;font-family:var(--pa-font);color:var(--pa-ink);background:var(--pa-white);line-height:1.6;font-size:16px}
img{max-width:100%;height:auto;display:block}
a{color:var(--pa-violet-700);text-decoration:none}
a:hover{text-decoration:underline}
h1,h2,h3,h4{line-height:1.18;color:var(--pa-ink);margin:0 0 .5em;font-weight:700;letter-spacing:-.01em}
.pa-container{width:100%;max-width:var(--pa-maxw);margin:0 auto;padding:0 22px}
.pa-screen-reader{position:absolute!important;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap}
.pa-skip{position:absolute;left:-999px;top:0;background:var(--pa-ink);color:#fff;padding:10px 16px;z-index:100}
.pa-skip:focus{left:8px;top:8px}
.pa-accent{color:var(--pa-teal)}

/* HEADER */
.pa-header{position:sticky;top:0;z-index:50;background:rgba(255,255,255,.92);backdrop-filter:saturate(150%) blur(8px);border-bottom:1px solid var(--pa-border)}
.pa-header__inner{display:flex;align-items:center;gap:20px;height:68px}
.pa-brand{display:flex;align-items:center;gap:9px;color:var(--pa-ink);font-weight:700;font-size:18px}
.pa-brand:hover{text-decoration:none}
.pa-brand__mark{display:grid;place-items:center;width:34px;height:34px;border-radius:9px;background:linear-gradient(135deg,var(--pa-teal),var(--pa-violet));color:#fff}
.pa-brand__text strong{color:var(--pa-teal)}
.pa-nav{margin-left:auto}
.pa-nav__list{display:flex;gap:6px;list-style:none;margin:0;padding:0}
.pa-nav__list a{display:block;padding:9px 12px;border-radius:8px;color:var(--pa-ink-700);font-weight:500;font-size:15px}
.pa-nav__list a:hover{background:var(--pa-teal-050);color:var(--pa-teal-700);text-decoration:none}
.pa-nav__toggle{display:none}
.pa-search{display:flex;align-items:center;gap:8px;background:var(--pa-surface);border:1px solid var(--pa-border);border-radius:999px;padding:8px 14px;min-width:210px}
.pa-search__icon{display:grid;place-items:center;color:var(--pa-slate-400)}
.pa-search input{border:0;background:transparent;outline:none;font:inherit;font-size:14px;width:100%;color:var(--pa-ink)}

/* HERO */
.pa-hero{background:radial-gradient(1200px 400px at 80% -10%,var(--pa-violet-050),transparent),linear-gradient(180deg,#fbfdfe,var(--pa-surface));border-bottom:1px solid var(--pa-border)}
.pa-hero__inner{padding:74px 22px 64px;text-align:center}
.pa-eyebrow{display:inline-block;font-size:13px;font-weight:600;letter-spacing:.06em;text-transform:uppercase;color:var(--pa-teal-700);background:var(--pa-teal-050);padding:6px 12px;border-radius:999px;margin:0 0 18px}
.pa-hero__title{font-size:clamp(2.1rem,5vw,3.6rem);margin:0 0 16px}
.pa-hero__sub{max-width:620px;margin:0 auto 28px;color:var(--pa-slate);font-size:clamp(1rem,2.2vw,1.18rem)}
.pa-hero__search{display:flex;align-items:center;gap:8px;max-width:560px;margin:0 auto;background:#fff;border:1px solid var(--pa-border);border-radius:999px;padding:8px 8px 8px 16px;box-shadow:var(--pa-shadow)}
.pa-hero__search .pa-search__icon{color:var(--pa-teal)}
.pa-hero__search input{flex:1;border:0;outline:none;font:inherit;font-size:16px;background:transparent;color:var(--pa-ink)}
.pa-hero__search button{border:0;background:var(--pa-violet);color:#fff;font-weight:600;padding:11px 22px;border-radius:999px;cursor:pointer;font-size:15px}
.pa-hero__search button:hover{background:var(--pa-violet-700)}
.pa-hero__micro{margin:18px 0 0;font-size:13px;color:var(--pa-slate-400);letter-spacing:.02em}

/* STATS */
.pa-stats{background:var(--pa-ink);color:#fff}
.pa-stats__grid{display:grid;grid-template-columns:repeat(3,1fr);gap:8px;padding:26px 22px}
.pa-stat{text-align:center;padding:6px 10px}
.pa-stat__value{display:block;font-size:1.9rem;font-weight:800;color:#fff;letter-spacing:-.02em}
.pa-stat__label{display:block;font-weight:600;font-size:.95rem;margin-top:2px}
.pa-stat__note{display:block;font-size:.8rem;color:var(--pa-slate-400);margin-top:3px}

/* SECTIONS */
.pa-section{padding:64px 0}
.pa-section--alt{background:var(--pa-surface);border-top:1px solid var(--pa-border);border-bottom:1px solid var(--pa-border)}
.pa-section__head{text-align:center;max-width:640px;margin:0 auto 38px}
.pa-section__head h2{font-size:clamp(1.6rem,3.4vw,2.2rem)}
.pa-section__head p{color:var(--pa-slate);margin:0;font-size:1.05rem}
.pa-section__more{text-align:center;margin-top:34px}

/* CARDS — categories */
.pa-cards{display:grid;gap:18px}
.pa-cards--cat{grid-template-columns:repeat(3,1fr)}
.pa-cat{display:flex;flex-direction:column;gap:6px;padding:24px;background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius);box-shadow:var(--pa-shadow);transition:transform .14s ease,border-color .14s ease}
.pa-cat:hover{text-decoration:none;transform:translateY(-3px);border-color:var(--pa-teal)}
.pa-cat__icon{font-size:1.7rem}
.pa-cat__name{font-weight:700;font-size:1.15rem;color:var(--pa-ink)}
.pa-cat__blurb{color:var(--pa-slate);font-size:.95rem}
.pa-cat__go{margin-top:6px;color:var(--pa-teal-700);font-weight:600;font-size:.9rem}

/* CARDS — compounds */
.pa-cards--compound{grid-template-columns:repeat(4,1fr)}
.pa-compound{display:flex;flex-direction:column;gap:5px;padding:20px;background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius);box-shadow:var(--pa-shadow);transition:transform .14s ease,border-color .14s ease}
.pa-compound:hover{text-decoration:none;transform:translateY(-3px);border-color:var(--pa-violet)}
.pa-compound__name{font-weight:800;font-size:1.2rem;color:var(--pa-ink)}
.pa-compound__aka{font-size:.82rem;color:var(--pa-slate-400)}
.pa-compound__sum{font-size:.9rem;color:var(--pa-slate);margin-top:4px;flex:1}
.pa-compound__verified{margin-top:8px;font-size:.8rem;font-weight:600;color:var(--pa-green)}
.pa-chip{align-self:flex-start;font-size:.72rem;font-weight:600;padding:3px 9px;border-radius:999px;background:var(--pa-teal-050);color:var(--pa-teal-700);text-transform:none}
.pa-chip--anti-aging,.pa-chip--weight-loss{background:var(--pa-violet-050);color:var(--pa-violet-700)}

/* CARDS — guides */
.pa-cards--guide{grid-template-columns:repeat(3,1fr)}
.pa-guide{display:flex;flex-direction:column;gap:5px;padding:18px 20px;background:#fff;border:1px solid var(--pa-border);border-left:3px solid var(--pa-violet);border-radius:var(--pa-radius-sm);transition:transform .14s ease,border-left-color .14s ease,box-shadow .14s ease}
.pa-guide:hover{text-decoration:none;transform:translateY(-2px);border-left-color:var(--pa-teal);box-shadow:var(--pa-shadow)}
.pa-guide__title{font-weight:700;color:var(--pa-ink);font-size:1.02rem}
.pa-guide__blurb{font-size:.9rem;color:var(--pa-slate);flex:1}
.pa-guide__go{margin-top:6px;font-size:.84rem;font-weight:600;color:var(--pa-violet-700)}

/* STEPS */
.pa-steps{display:grid;grid-template-columns:repeat(3,1fr);gap:18px;list-style:none;margin:0;padding:0;counter-reset:s}
.pa-step{position:relative;padding:28px 24px;background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius);box-shadow:var(--pa-shadow)}
.pa-step__n{display:grid;place-items:center;width:40px;height:40px;border-radius:11px;background:linear-gradient(135deg,var(--pa-teal),var(--pa-violet));color:#fff;font-weight:800;margin-bottom:12px}
.pa-step h3{margin:0 0 6px;font-size:1.2rem}
.pa-step p{margin:0;color:var(--pa-slate)}

/* CTA */
.pa-cta{background:linear-gradient(120deg,var(--pa-teal),var(--pa-teal-700) 55%,var(--pa-violet-700));color:#fff}
.pa-cta__inner{display:flex;align-items:center;justify-content:space-between;gap:24px;padding:46px 22px;flex-wrap:wrap}
.pa-cta h2{color:#fff;margin:0 0 6px}
.pa-cta p{margin:0;color:rgba(255,255,255,.85)}
.pa-btn{display:inline-block;font-weight:600;padding:12px 24px;border-radius:999px;cursor:pointer;border:1px solid transparent}
.pa-btn:hover{text-decoration:none}
.pa-btn--accent{background:#fff;color:var(--pa-teal-700)}
.pa-btn--accent:hover{background:#f0f0ff}
.pa-btn--ghost{border-color:var(--pa-border);color:var(--pa-teal-700);background:#fff}
.pa-btn--ghost:hover{border-color:var(--pa-teal)}

/* DISCLAIMER BAND */
.pa-disclaimerband{background:#fffbeb;border-top:1px solid #fde68a;border-bottom:1px solid #fde68a}
.pa-disclaimerband p{margin:0;padding:14px 0;font-size:.86rem;color:#92660b}
.pa-disclaimerband__tag{display:inline-block;font-weight:700;font-size:.72rem;text-transform:uppercase;letter-spacing:.04em;color:#fff;background:var(--pa-amber);padding:2px 8px;border-radius:6px;margin-right:8px;vertical-align:middle}

/* FOOTER */
.pa-footer{background:var(--pa-ink);color:#cbd5e1}
.pa-footer__grid{display:grid;grid-template-columns:2fr 1fr 1fr 1fr 1fr;gap:30px;padding:54px 22px 34px}
.pa-brand--footer .pa-brand__text{color:#fff}
.pa-footer__tag{color:var(--pa-slate-400);font-size:.92rem;margin:12px 0 0;max-width:32ch}
.pa-footer__col h4{color:#fff;font-size:.8rem;text-transform:uppercase;letter-spacing:.06em;margin:0 0 14px}
.pa-footer__col ul{list-style:none;margin:0;padding:0;display:grid;gap:9px}
.pa-footer__col a{color:#cbd5e1;font-size:.92rem}
.pa-footer__col a:hover{color:#fff}
.pa-footer__bar{border-top:1px solid #1e293b}
.pa-footer__barinner{display:flex;justify-content:space-between;gap:14px;padding:18px 22px;flex-wrap:wrap}
.pa-footer__bar p{margin:0;font-size:.82rem;color:var(--pa-slate-400)}
.pa-footer__legal a{color:var(--pa-slate-400)}

/* PROSE (fallback pages) */
.pa-prose{max-width:760px}
.pa-postlist{line-height:2}

/* ===== COMPOUND PROFILE ===== */
.pa-crumbs{background:var(--pa-surface);border-bottom:1px solid var(--pa-border);font-size:.86rem}
.pa-crumbs .pa-container{padding-top:13px;padding-bottom:13px}
.pa-crumbs a{color:var(--pa-slate)}
.pa-crumbs span{color:var(--pa-slate-400);margin:0 4px}
.pa-crumbs__here{color:var(--pa-ink);font-weight:600}
.pa-profile__grid{display:grid;grid-template-columns:1fr 320px;gap:42px;padding-top:40px;padding-bottom:52px;align-items:start}
.pa-profile__head{margin-bottom:18px}
.pa-profile__head h1{font-size:clamp(2rem,4vw,2.8rem);margin:10px 0 6px}
.pa-profile__aka{color:var(--pa-slate-400);font-size:.92rem;margin:0}
.pa-aeo{background:var(--pa-teal-050);border:1px solid #bfe3e6;border-left:4px solid var(--pa-teal);border-radius:var(--pa-radius-sm);padding:18px 20px;margin:0 0 30px}
.pa-aeo__tag{display:inline-block;font-size:.72rem;font-weight:700;text-transform:uppercase;letter-spacing:.05em;color:var(--pa-teal-700);margin-bottom:6px}
.pa-aeo p{margin:0;font-size:1.08rem;color:var(--pa-ink-700);line-height:1.65}
.pa-block{margin:0 0 38px}
.pa-block h2{font-size:1.5rem;padding-bottom:8px;border-bottom:2px solid var(--pa-border);margin-bottom:16px}
.pa-block h3{font-size:1.1rem;margin:18px 0 6px}
.pa-prose{font-family:var(--pa-serif);color:var(--pa-ink-700);font-size:1.05rem}
.pa-prose p{margin:0 0 14px}
.pa-benefits{list-style:none;margin:0 0 8px;padding:0;display:grid;gap:12px}
.pa-benefits li{display:flex;flex-direction:column;gap:2px;padding:14px 16px;background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius-sm)}
.pa-benefits strong{color:var(--pa-ink)}
.pa-benefits span{color:var(--pa-slate);font-size:.96rem}
.pa-mech{margin-top:14px;padding:16px 18px;background:var(--pa-surface);border-radius:var(--pa-radius-sm)}
.pa-mech h3{margin:0 0 6px}
.pa-mech p{margin:0;color:var(--pa-ink-700)}
.pa-cites{list-style:none;margin:14px 0 0;padding:0;display:grid;gap:10px}
.pa-cites li{padding:12px 14px;background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius-sm)}
.pa-cites a{font-weight:600}
.pa-cites__yr{color:var(--pa-slate-400);font-weight:400}
.pa-cites__src{display:block;font-size:.78rem;color:var(--pa-slate-400);margin-top:3px}
.pa-stacks{display:grid;grid-template-columns:1fr 1fr;gap:12px}
.pa-stackcard{display:flex;flex-direction:column;gap:3px;padding:15px 16px;background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius-sm)}
.pa-stackcard:hover{text-decoration:none;border-color:var(--pa-violet)}
.pa-stackcard__name{font-weight:700;color:var(--pa-ink)}
.pa-stackcard__note{font-size:.88rem;color:var(--pa-slate)}
.pa-faq__item{border:1px solid var(--pa-border);border-radius:var(--pa-radius-sm);margin-bottom:10px;background:#fff;overflow:hidden}
.pa-faq__item summary{cursor:pointer;padding:15px 18px;font-weight:600;color:var(--pa-ink);list-style:none;position:relative}
.pa-faq__item summary::-webkit-details-marker{display:none}
.pa-faq__item summary::after{content:"+";position:absolute;right:18px;color:var(--pa-teal);font-weight:700}
.pa-faq__item[open] summary::after{content:"–"}
.pa-faq__a{padding:0 18px 16px;color:var(--pa-slate)}
.pa-faq__a p{margin:0}
/* sidebar */
.pa-factcard,.pa-buybox{background:#fff;border:1px solid var(--pa-border);border-radius:var(--pa-radius);box-shadow:var(--pa-shadow);padding:20px}
.pa-factcard{position:sticky;top:84px;margin-bottom:18px}
.pa-factcard h3,.pa-buybox h3{font-size:1.05rem;margin:0 0 12px}
.pa-factcard dl{margin:0}
.pa-factcard__row{display:flex;justify-content:space-between;gap:12px;padding:9px 0;border-bottom:1px solid var(--pa-surface)}
.pa-factcard__row:last-child{border-bottom:0}
.pa-factcard dt{color:var(--pa-slate);font-size:.88rem}
.pa-factcard dd{margin:0;font-weight:600;font-size:.88rem;text-align:right;color:var(--pa-ink)}
.pa-factcard__src{font-size:.74rem;color:var(--pa-slate-400);margin:12px 0 0}
.pa-buybox p{color:var(--pa-slate);font-size:.92rem;margin:0 0 14px}
.pa-btn--full{display:block;text-align:center}
.pa-legalnote{font-size:.86rem;color:var(--pa-slate);background:var(--pa-surface);border:1px solid var(--pa-border);border-radius:var(--pa-radius-sm);padding:14px 16px;margin:0 0 40px}
.pa-related{margin-top:8px}

/* ===== EDITORIAL GUIDE ===== */
.pa-guide-page__wrap{max-width:760px;margin:0 auto;padding-top:36px;padding-bottom:52px}
.pa-guide-page__head{margin-bottom:18px}
.pa-guide-page__head h1{font-size:clamp(1.9rem,4vw,2.6rem);margin:10px 0 8px}
.pa-byline{color:var(--pa-slate);font-size:.9rem;margin:0}
.pa-byline strong{color:var(--pa-ink-700)}
.pa-takeaways{background:var(--pa-violet-050);border:1px solid #d8d2f7;border-radius:var(--pa-radius);padding:20px 24px;margin:0 0 28px}
.pa-takeaways h2{font-size:1.1rem;margin:0 0 10px;border:0;padding:0}
.pa-takeaways ul{margin:0;padding-left:20px;display:grid;gap:7px}
.pa-takeaways li{color:var(--pa-ink-700)}
.pa-guide-body{font-size:1.06rem}
.pa-guide-body h2{font-family:var(--pa-font);font-size:1.45rem;margin:30px 0 12px;padding-bottom:8px;border-bottom:2px solid var(--pa-border)}
.pa-guide-body h3{font-family:var(--pa-font);font-size:1.15rem;margin:20px 0 6px}
.pa-guide-body ul,.pa-guide-body ol{padding-left:22px;margin:0 0 14px}
.pa-guide-body li{margin:0 0 6px}
.pa-relguides .pa-cards--guide{grid-template-columns:1fr 1fr}
.pa-guide-cta{margin-top:34px;padding:26px;background:var(--pa-surface);border:1px solid var(--pa-border);border-radius:var(--pa-radius);text-align:center}
.pa-guide-cta p{margin:0 0 14px;color:var(--pa-ink-700);font-weight:500}
.pa-guide-cta__btns{display:flex;gap:10px;justify-content:center;flex-wrap:wrap}

/* RESPONSIVE */
@media (max-width:980px){
  .pa-profile__grid{grid-template-columns:1fr;gap:8px}
  .pa-factcard{position:static}
  .pa-profile__side{order:-1}
  .pa-cards--compound{grid-template-columns:repeat(2,1fr)}
  .pa-cards--guide{grid-template-columns:repeat(2,1fr)}
  .pa-footer__grid{grid-template-columns:1fr 1fr 1fr;row-gap:34px}
  .pa-footer__brand{grid-column:1/-1}
}
@media (max-width:760px){
  .pa-search{display:none}
  .pa-nav{margin-left:auto}
  .pa-nav__toggle{display:grid;place-items:center;width:42px;height:42px;border:1px solid var(--pa-border);border-radius:9px;background:#fff;cursor:pointer}
  .pa-nav__bars,.pa-nav__bars::before,.pa-nav__bars::after{content:"";display:block;width:18px;height:2px;background:var(--pa-ink);border-radius:2px;position:relative}
  .pa-nav__bars::before{position:absolute;top:-6px}.pa-nav__bars::after{position:absolute;top:6px}
  .pa-nav__list{position:absolute;left:0;right:0;top:68px;flex-direction:column;gap:0;background:#fff;border-bottom:1px solid var(--pa-border);padding:8px 14px 14px;display:none;box-shadow:var(--pa-shadow)}
  .pa-nav__list.is-open{display:flex}
  .pa-nav__list a{padding:13px 10px}
  .pa-cards--cat,.pa-cards--compound,.pa-cards--guide,.pa-steps,.pa-stats__grid{grid-template-columns:1fr}
  .pa-stats__grid{gap:18px}
  .pa-footer__grid{grid-template-columns:1fr 1fr}
}